Richard Selinfreund, PhD
Associate Professor of Physiology and Pathology, Pathology

Room 311
Phone: 575-674-2338
Email: rselinfreund@bcomnm.org
Department: Department of Physiology & Pathology

Education

Los Alamos National Laboratory/New Mexico State University                               1985 – 1988

Doctor of Philosophy (PhD), Biology, Physics and Cell Biology

Studied at the National Flow Cytometry Center, Los Alamos New Mexico. Our work centered around the role of growth factors on cellular transformation. The combination of flow cytometry and fluorescent dyes were used to measure cell cycle progression related to cancer.

Activities and Societies: Society for Neurosciences

Vanderbilt University School of Medicine, Howard Hughes Medical Institute.

Yale University, School of Medicine New Haven, CT
Dept. of Neuropharmacology, Fellowship, Research Scientist

Research Interests

Dr. Selinfreund, is a PhD Medical Pathologist (trained at Vanderbilt and Yale Schools of Medicine). His work focuses on developing natural food sources that impact Global Health: Specifically, in the areas of: Infant Development, Child Nutrition, and Metabolic Disease.

Research Interests:

  • Computer-Modelling Guided Development of Clinically Important Bio-Active Molecules for the treatment of Metabolic Disease, Cancer and Alzheimer’s Disease.
  • Clinical Comparison of Metabolically Balanced Fluids on Glucose, Insulin and HbA1c Levels.
  • Youth Empowerment Programs (Pueblo of Jemez) & Burrell College of Osteopathic Medicine (BCOM). Career Pathway Program.

Core Research Programs:

  • Platform to accelerate and measure sunlight damage to bioactive and nutritional compounds
  • Development of stable and bioactive compounds (high through-put screening).
  • All natural beverages– developed all natural beverages that contain non high fructose corn syrup and natural colors.

Current Facilities & Funding:

Dr. Selinfreund has a fully funded laboratory focused on global health and nutrition problems:

  1.  Developed proprietary processing-aid for Pecans [Successful in Market Product]
  2. Awarded a contract to remove pesticides from Chile [Commercial Phase ]
  3. Filed Patents (Nov. 2016/2017) for all natural, non HFCS based soft drink and food formulas [June 25th, 2018 Launch]

Selected Publications

PATENTS

Glucose beverage comprising exogenous flavor source and color

Priority 2016-10-18 • Filing 2017-10-18 • Publication 2018-04-26

The present invention is directed to glucose containing beverages that closely match the sweetness, caloric and satiety sensations of sucrose-containing or high fructose corn syrup-containing beverages currently available to consumers but assist to ameliorate various disease conditions such as …

Nut shell coatings for improved processing and storage

 

Application WO2016210310A1 Richard Selinfreund Richard Selinfreund

Priority 2015-06-24 • Filing 2016-06-24 • Publication 2016-12-29

The present invention is directed to an integrated system of improving nut product safety, quality and production costs. Formulations and methods are provided for reducing pathogen contamination of nuts, improving storage stability of …

Compositions and methods for improving diagnosis

 

Application WO2014062819A1 Richard H. Selinfreund Companion Diagnostics Inc.

Priority 2012-10-16 • Filing 2013-10-16 • Publication 2014-04-24

The invention provides compositions and methods for improving diagnosis. Specifically, the invention provides compositions and methods for enhancing the sensitivity or accuracy of a diagnostic test that uses a urine sample. Hospitals, …

Remote circuit locking switch system

 

Application US20130339752A1 Richard H. Selinfreund Companion Diagnostics Inc.

Priority 2009-04-03 • Filing 2013-08-13 • Publication 2013-12-19

A method and apparatus for remotely controlling access to the components of an optically interconnected information processing infrastructure is presented. Access to the infrastructure is controlled independently of the infrastructure …

Methods of determining stabilization compounds for predictive biomarkers

 

Application US20140155282A1 Richard H. Selinfreund Companion Diagnostics, Inc.

Priority 2010-02-10 • Filing 2013-06-06 • Publication 2014-06-05

Methods of determining stabilization compounds for predictive biomarkers. According to at least one embodiment of a method of the present disclosure, the method comprises introducing a diagnostic marker and a stabilization agent to a …

Devices, systems, and methods for fecal analysis

 

Application WO2012088330A3 Richard H. Selinfreund Companion Diagnostics Inc.

Priority 2010-12-22 • Filing 2011-12-21 • Publication 2012-09-13

Herein are presented devices, systems, and methods for biomarker stabilization and analysis, including formulations which function to preserve the level of markers in body fluids from enzymatic alteration and degradation. In embodiments …

Devices and washes for biomarker stabilization

 

Application WO2012078260A1 Richard H. Selinfreund Companion Diagnostics Inc.

Priority 2010-10-28 • Filing 2011-10-28 • Publication 2012-06-14

Herein are disclosed compositions, washes, rinses, devices, systems and methods for biomarker stabilization, in part in bodily fluids, as well as methods and formulations for improving the sampling and testing of fluids for biomarkers.

Biological and chemical test media and system

 

Application US20120065896A1 Richard H. Selinfreund Selinfreund Richard H

Priority 2007-12-04 • Filing 2011-09-21 • Publication 2012-03-15

An apparatus and method for performing medical, biological or chemical tests in the field is disclosed. In some embodiments, the test media comprises a special purpose optical disc which is read, after application of the test specimen and …

Devices, systems, and methods for biomarker stabilization

 

Application WO2011127467A1 Richard H. Selinfreund Companion Diagnostics, Inc.

Priority 2010-04-09 • Filing 2011-04-11 • Publication 2011-10-13

Devices, systems and methods for biomarker stabilization. In at least one embodiment of a stabilizing system, the system comprises a stabilizing agent useful to completely or substantially prevent degradation or inactivation of a …

Electronic backbone for medicine infrastructure

 

Application EP2273399A3 Richard Selinfreund Sony Corporation

Priority 2009-06-23 • Filing 2010-06-23 • Publication 2015-09-30

Embodiments of the invention relate to the association of a non-guessable, unique ID with a user and the automatic or electronic referral of user ID to a medical service provider, without revealing private medical information. After the …

Printing bio-reactive materials

 

Application US20100208006A1 Richard Selinfreund Sony Corporation

Priority 2009-02-18 • Filing 2010-02-17 • Publication 2010-08-19

A method for printing one or more desired features on a polymeric substrate. In an example embodiment, the method includes receiving an ink that includes a bio-reactive indicator material, and employing a piezoelectric printhead to …

Diagnostic system with portable collection housing

 

Application WO2010028298A1 Richard H. Selinfreund Sony Dadc

Priority 2008-09-04 • Filing 2009-09-04 • Publication 2010-03-11

Disclosed is a convenient panel of tests, that may be in disposable form, that allows the user to assess current health status or projected health status.

Biological and chemical test media and system

 

Application CA2677484A1 Richard H. Selinfreund Richard H. Selinfreund

Priority 2008-09-04 • Filing 2009-09-02 • Publication 2010-03-04

An apparatus and method for performing medical, biological or chemical tests in the field is disclosed. In some embodiments, the test media comprises a special purpose optical disc which is read, after application of the test specimen and …

Piracy protected recording media

 

Application US20090035539A1 Richard H. Selinfreund Verification Technologies, Inc.

Priority 2005-04-18 • Filing 2008-10-14 • Publication 2009-02-05

An optical medium piracy system employing a state-change material in association with a digital data indicia, wherein when state-change material is activated to change state, the optical medium moves from an unreadable to a readable …

Product packaging including digital data

 

Application US20090008452A1 Richard H. Selinfreund Verification Technologies, Inc.

Priority 2000-06-30 • Filing 2008-09-11 • Publication 2009-01-08

Light sensitive materials applied in shipping materials, including security seals and tear tape, for authentication, discrimination and recognition of items.

Material for optical medium copy-protection transiently reacting to reader beam

 

Application JP2008176925A Richard H Selinfreund Verification Technologies Inc

Priority 2002-06-17 • Filing 2008-04-08 • Publication 2008-07-31

<P>PROBLEM TO BE SOLVED: To provide an copy-protected optical medium using an optical state change protection material, and an excellent method for protecting copy. <P>SOLUTION: There are provided a method and system for providing copy- …

Changing light absorption by disruption of conjugation

 

Application US20080193873A1 Richard H. Selinfreund Verification Technologies, Inc.

Priority 2002-06-17 • Filing 2008-03-24 • Publication 2008-08-14

Copy-protected optical medium utilizing a composition comprising a transient optical state change security materials constrained to change the optical state light absorption at a wavelength of about 400 nm and an electron transfer agent.

Copy Protection for Video Content Contained in the VOB File Structure

 

Application US20080212952A1 Richard H. Selinfreund Verification Technologies, Inc.

Priority 2005-01-13 • Filing 2008-02-25 • Publication 2008-09-04

A digital video optical recording medium comprising an optical state change material in the VOB file structure.

Content Replication Deterrent Method on Optical Discs

 

Application US20080187135A1 Richard H. Selinfreund Verification Technologies, Inc.

Priority 2002-04-10 • Filing 2008-02-21 • Publication 2008-08-07

Through embodiments, an optical medium is disclosed which includes features for presenting alphanumeric text and graphics which can be made discernable or indiscernible.

Method and apparatus for controlling access to storage media

 

Application US20080130460A1 Richard H. Selinfreund Verification Technologies, Inc.

Priority 2000-08-03 • Filing 2008-02-08 • Publication 2008-06-05

In embodiments, a method and apparatus for controlling access to a storage medium, such as an optically readable medium. Light sensitive or other materials that are adapted to change state and affect reading of a storage medium are used …

Read-side anti-theft discs

 

Application EP2102863A4 Richard H Selinfreund Verification Technologies Inc

Priority 2006-12-27 • Filing 2007-12-27 • Publication 2010-01-27

Read-side anti-theft optical discs and method of manufacturing read-side anti- …

 

Application US20080165669A1 Richard Selinfreund Sony Corporation

Priority 2007-01-05 • Filing 2007-12-26 • Publication 2008-07-10

The invention relates to methods for manufacturing an optical devices and optical devices incorporating optical blocking material on the read-side surface of the optical disc. A protective layer and an optical blocking material are …

Method for Uniquely Identifying Optical Media

 

Application US20080172686A1 Richard H. Selinfreund Selinfreund Richard H

Priority 2007-01-16 • Filing 2007-12-03 • Publication 2008-07-17

A method for recording a unique identifier onto an optical medium said method comprising the stops of obtaining a manufactured optical medium and ink jet printing onto the read-side surface of said medium one or more light-changeable …

Secured Disc

 

Application US20090132421A1 Richard H. Selinfreund Selinfreund Richard H

Priority 2006-12-12 • Filing 2007-11-21 • Publication 2009-05-21

A secured disc.

Storage Media Access Control Method and System

 

Application US20080066090A1 Richard Selinfreund Verification Technologies, Inc.

Priority 2000-06-30 • Filing 2007-10-24 • Publication 2008-03-13

A computer-readable medium having material at a select position therein and containing instructions for controlling an optical reader to cause the optical reader to re-read the position having the material one or more times to elicit a …

Product Packaging Including Digital Data

 

Application US20080011853A1 Richard Selinfreund Verification Technologies, Inc.

Priority 2000-06-30 • Filing 2007-07-02 • Publication 2008-01-17

Light sensitive materials applied in shipping materials, including security seals and tear tape, for authentication, discrimination and recognition of items.

Optical disc carrying case with activation window

 

Application WO2008002928A3 Richard H Selinfreund Veriloc Llc

Priority 2006-06-27 • Filing 2007-06-26 • Publication 2008-10-30

A storage case of storing optical digital data storage media, the case including a cover with a defined area therein that permits transmission of certain energy to the medium stored therein while the area of the cover outside of the …

Coating system for piracy-protected optical medium

 

Application WO2008002923A3 Richard H Selinfreund Veriloc Llc

Priority 2006-06-27 • Filing 2007-06-26 • Publication 2008-08-21

A piracy protection digital recording medium comprising a polymeric layer incorporating an optical state change material in conjunction with a cationic photoinitiator.

Authenticating polymeric film

 

Application EP2021171A2 Richard H. Selinfreund Verification Technologies, Inc

Priority 2006-05-30 • Filing 2007-05-30 • Publication 2009-02-11

A piracy protection digital recording medium comprising an optical recording medium coated with a polymeric film containing authentication state change material therein, the authentication state change material being readable by a digital …

Formulations useful in the production of anti-shrink-copy-protected digital …

 

Application EP2013010A2 Richard H. Selinfreund Verificatin Technologies, Inc

Priority 2006-04-28 • Filing 2007-04-27 • Publication 2009-01-14

Formulations useful in the manufacture of anti-theft and copy-protected digital recording media, in an embodiment comprising a state change material in a hardcoat polymer.

Optical media device with minipulatable read capability

 

Application CA2648241A1 Richard Selinfreund Veriloc Llc

Priority 2006-03-31 • Filing 2007-03-30 • Publication 2007-10-11

An optical media device comprises a mask layer (16) placed over a data layer (14), and that includes a chemical ingredients designed to render the data layer unreadable by an optical reader in a first initial state, and allow the data …

Processes for preparing novel methylene blue derivative

 

Application US20070129543A1 Richard Selinfreund Verfication Technologies, Inc.

Priority 2002-06-17 • Filing 2007-01-31 • Publication 2007-06-07

Methods for the preparation of 7-(dipropylamino)pheno-thiazin-3-ylidene]-dipropylamine

Data-protected digital recording medium

 

Application WO2007082239A2 Richard H. Selinfreund Verification Technologies, Inc.

Priority 2006-01-10 • Filing 2007-01-10 • Publication 2007-07-19

In one embodiment, a digital recording medium having digital datum indicia thereon readable by a reader producing a read-wave, the digital recording medium comprising: a photochrome materia] activatable from a first optical state to a …

Anti-theft system for optical products

 

Application US20070214507A1 Richard Selinfreund Selinfreund Richard H

Priority 2005-11-23 • Filing 2006-11-13 • Publication 2007-09-13

A system for reducing supply chain theft comprising a medium having a state-change material associated therewith that is activatable from a first detectable state to a second detectable state by an activating wave that is energetically …

Hard-copy for anti-shrink – anti-copy optical medium

 

Application US20070212512A1 Richard Selinfreund Selinfreund Richard H

Priority 2005-11-01 • Filing 2006-11-01 • Publication 2007-09-13

A recording medium configured to unmask read of data thereon, or a portion of data thereon, upon an optical state change of a state change material on or in the recording medium, said recording medium having a code stored thereon which …

Method for producing an anti-theft/anti-copy optical medium

 

Application EP1934974A2 Richard H. Selinfreund Verificatin Technologies, Inc

Priority 2005-10-12 • Filing 2006-10-12 • Publication 2008-06-25

A method for producing a theft-protected optical medium printing onto a portion an optical medium state change material having at least a first unactivated state and a second activated state, said portion of said optical medium and said …

Security system for transactions

 

Application WO2007033285A2 Richard H. Selinfreund Uniloc/Veriloc, Llc

Priority 2005-09-13 • Filing 2006-09-13 • Publication 2007-03-22

Systems and methods for confirming the authorization of a person seeking to make a transaction over a computer network system using algorithms to determine whether a digital recording medium has a fingerprint associated with a medium …

Security system for transactions

 

Application US20070107045A1 Richard Selinfreund Uniloc/Veriloc, Llc

Priority 2005-09-13 • Filing 2006-09-13 • Publication 2007-05-10

Systems and methods for confirming the authorization of a person seeking tomake a transaction over a computer network system using algorithms to determine whether a digital recording medium has a fingerprint associated with a medium …

Selectively enabling playback of content on an optical medium

 

Application EP1917597A4 Richard Selinfreund Sony Dadc Us Inc

Priority 2005-08-24 • Filing 2006-08-23 • Publication 2010-01-13

Selectively enabling playback of content on an optical medium

 

Application WO2007025076A8 Richard Selinfreund Sony Dadc Us Inc.

Priority 2005-08-24 • Filing 2006-08-23 • Publication 2007-04-12

A system for selectively inhibiting unauthorized use of an optical device. In an illustrative embodiment, the system implements an optical-device play-prevention system and copy-prevention system. The system includes a first set of data …

Method and system for optical disk copy-protection

 

Application US20060203700A1 Richard Selinfreund Verification Technologies, Inc.

Priority 2003-02-06 • Filing 2006-05-16 • Publication 2006-09-14

A method and system for providing copy-protected optical medium using a substrate having information stored thereon in information pits and information lands, wherein the information lands comprise lands in two different planes.

System and method for selectively enabling or disabling an optical device

 

Application WO2006116493A2 Richard Selinfreund Sony Dadc Us Inc.

Priority 2005-04-25 • Filing 2006-04-25 • Publication 2006-11-02

A system for selectively enabling or disabling an optical device. In an illustrative embodiment, the system implements an optical-device theft-prevention system. The theft-prevention system includes a material that is selectively …

Ultraviolet activating system for preventing digital piracy from recording …

 

Application CA2604237A1 Richard H. Selinfreund Veriloc, Llc

Priority 2005-04-18 • Filing 2006-04-14 • Publication 2006-10-26

An optical medium piracy method and system employing a ultraviolet-sensitive state- change material capable of changing state upon activation with a wavelength of ultraviolet between 253 +/- 25 nm to 365 +/- 25 nm, the state-change …

Optical disc registration system

 

Application CA2603501A1 Richard H. Selinfreund Richard H. Selinfreund

Priority 2005-04-05 • Filing 2006-04-05 • Publication 2006-10-12

The instant application consists of a registration system for an optical medium. The system locks the optical medium through the use of a unique code comprising optically readable indicia therein, to the processing device upon which it is …

Optical machine locking method and system

 

Application WO2006053280A2 Richard H. Selinfreund Selinfreund Richard H

Priority 2004-11-10 • Filing 2005-11-10 • Publication 2006-05-18

A method for assuring the authorized nature of encrypted transmissions between a plurality of communicators using a plurality of stand-alone communication processing devices, said method comprising the steps of: a) determining unique …

Changing light absorption by disruption of conjugation

 

Application WO2006036885A2 Richard H. Selinfreund Verification Technologies, Inc.

Priority 2004-09-24 • Filing 2005-09-23 • Publication 2006-04-06

Copy-protected optical medium utilizing a composition comprising a transient optical state change security materials constrained to change the optical state light absorption at a wavelength of about 400 nm and an electron transfer agent.

Changing light absorption by disruption of conjugation

 

Grant US7368221B2 Richard H. Selinfreund Verification Technologies, Inc.

Priority 2002-06-17 • Filing 2005-09-23 • Grant 2008-05-06 • Publication 2008-05-06

Copy-protected optical medium utilizing a composition comprising a transient optical state change security materials constrained to change the optical state light absorption at a wavelength of about 400 nm and an electron transfer agent.

Data storage in optical discs

 

Application US20110149705A1 Richard H. Selinfreund Verification Technologies, Inc.

Priority 2000-06-30 • Filing 2005-09-07 • Publication 2011-06-23

A device for preventing and controlling copying of data from an optical storage disc utilizing physical modifications in or on a storage capable optical disc. Also described is, a method for authenticating and controlling reading or …

Copy protected optical storage discs

 

Application WO2006031494A3 Richard H Selinfreund Verification Technologies Inc

Priority 2004-09-10 • Filing 2005-09-07 • Publication 2006-07-27

The optical media include light sensitive compounds applied either uniformly or in discrete locations on or in an optical recording medium. A layer (400) of light sensitive material is shown in figure 4 as preventing the readout of …

Devices and methods for product authentication and/or monitoring

 

Application WO2006009810A1 Richard Selinfreund Sun Chemical B.V.

Priority 2004-06-17 • Filing 2005-06-17 • Publication 2006-01-26

Aspects of the invention provide stabilized light-sensitive compounds and methods for their use in product authentication and/or monitoring. A light sensitive compound, such as a fluorescent dye, is combined with an isolating material to …

Laser reactive dyes for DVD copy protection system

 

Application US20050186382A1 Richard Selinfreund Verification Technologies, Inc.

Priority 2002-06-17 • Filing 2005-04-25 • Publication 2005-08-25

A method and system for providing copy-protected optical medium using transient optical state change security materials capable of changing optical state when exposed to a wavelength of about 630 nm to about 660 nm and software code to …